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Researchers at UVA Health, part of the University of Virginia, have made a significant discovery suggesting that an existing antiviral drug could serve as a preventative measure against Alzheimer’s disease. This revelation could profoundly impact the future of dementia treatment.
Doctors are examining a specific class of medications known as nucleoside reverse transcriptase inhibitors, or NRTIs, which are widely approved for the treatment of HIV infection. The UVA researchers found that individuals taking these drugs showed a notable decrease in the risk of developing Alzheimer’s disease, which currently affects millions globally.
According to Dr. Jayakrishna Ambati, the principal investigator of the study and a professor of ophthalmology, those on NRTIs experienced approximately a ten percent reduction in Alzheimer’s risk for each year of usage. This statistic signifies a potential breakthrough in how we address the aging population’s cognitive health.
The findings from this substantial research effort were published in the journal Alzheimer’s & Dementia, emphasizing the significance of this drug class in Alzheimer’s prevention.
The analysis was based on health insurance records spanning 24 years, involving data from around 270,000 patients. This extensive database provided a solid foundation for evaluating the relationship between NRTI usage and Alzheimer’s risk reduction.
The results revealed a